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Conclusions This case demonstrates that a deficiency in vitamin B12 can lead to severe macrocytic anemia and pancytopenia, both of which are significant yet treatable conditions

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Some research from Germany has shown that an even higher threshold (over 500 pg/mL) is necessary in early-to-mid pregnancy to maintain vitamin B12 levels throughout pregnancy, lactation, and to support an infants vitamin B12 status (via breast milk) through 6 months of age

Another study published in Clinical Medicine Insights: Endocrinology and Diabetes found a high prevalence of B12 deficiency in hypothyroid patients, with approximately 40% being deficient